Curriculum Vitae
Ciani Oriana is Associate Professor of Practice, Public Management and Policy Group, Health Economics & HTA at SDA Bocconi School of Management.
Her collaboration with SDA Bocconi began in 2010. She is leading the Epidemiology and Issues in Public Health module at the Master of International Health Care Management, Economics and Politics (MIHMEP) at SDA Bocconi. She has been teaching in numerous executive courses and has been involved in several training activities targeting professionals in the Healthcare industry.
Her research interests are centred around the use and impact of Health Technology Assessment (HTA) on decision-making in healthcare, on the methodological aspects of the evaluation of health technologies, particularly medical devices, and on the use of evidence synthesis techniques to inform policy decisions and health policies evaluation. She is also Research Fellow at the University of Exeter Medical School (UK) where she received her PhD with a thesis focusing on the evaluation of surrogate endpoints in HTA, which remains one of her main research topics. Oriana has been involved in many national and international research projects, often involving coordination among several partners, such as MedTecHTA (FP7 no. 305694), Mapping NCD (FP7 no. 602536) and, more recently, COMED (H2020 no.779306). Her research activities have been funded by external sources, both private and public.
Oriana is 2020 Fulbright Research Scholar at Yale School of Medicine and Yale School of Public Health. Oriana is author of several publications in HTA, health economics and health services research and reviewer for many international academic journals. She is member of the Early Career Committee of the European Health Economics Association (EuHEA), member of HTAi, of the International Association of Health Economics (iHEA), of the International Society of Pharmacoeconomics and Outcomes Research (ISPOR), of the Italian Association of Health Economics (AIES), of the International Federation for Medical and Biological Engineering (IFMBE) and of the Italian Association of Clinical Engineers (AIIC). Her paper in the International Journal of Health Technology Assessment (2015) on HTA practices for Medical Devices was awarded with the 2016 Egon Jonsson Award. She also received the Outstanding impact in Health and Wellbeing at the Exeter Impact Award Event (2013), Best Student Podium Presentation Award at the 16th ISPOR Annual European Meeting in Dublin (2013), the Young Researchers Award at 15th AIES Conference (2010).
Oriana holds a MSc in Biomedical Engineering from Politecnico di Milano and MSc in Healthcare Management and Economics from Bocconi University. She received her PhD from the Peninsula Technology Assessment Group (PenTAG), University of Exeter Medical School (UK).
Books
- Boscolo PR, Ciani O, Federici C, Furnari A, Tarricone R. Gli esiti di salute del Servizio Sanitario Nazionale (English: Health outcomes in the Italian NHS) In: CERGAS Bocconi (a cura di) Rapporto OASI 2017, Milano, Egea
- Tarricone R, Ciani O, Amatucci F, Armeni P, Borsoi L, Callea G, Costa F, Federici C, Torbica A. Programma nazionale HTA per dispositive medici: prove tecniche di implementazione (English: The implementation of the National HTA program for medical devices) In: CERGAS Bocconi (a cura di) Rapporto OASI 2017, Milano, Egea
- Ciani O, Taylor RS. Health Technology Assessment, In: Wiley StatsRef: Statistics Reference Online, 2017 doi: 10.1002/9781118445112.stat07941
- Ciani O, Torbica A. Myth #5: Healthcare Is Rightly Left to the Private Sector, for the Sake of Efficiency In: Adinolfi P, Borgonovi E (Eds.) The Myths of Health Care, Springer International Publishing AG, 2017
- Ciani O, Tarricone R, Torbica A. Programma nazionale HTA per dispositive medici: quali sfide per l’implementazione? (English: National HTA program for medical devices: the challenge of the implementation) In: CERGAS Bocconi (a cura di) Rapporto OASI 2016, Milano, Egea
- Boscolo PR, Ciani O, Tarricone R, Torbica A. La funzione di HTA nelle aziende sanitarie italiane: un potenziale ancora inutilizzato? (English: Hospital-based HTA: a potential to exploit?) In: CERGAS Bocconi (a cura di) Rapporto OASI 2015, Milano, Egea
- Ciani O, Tarricone R, Taylor RS. Comparing Drug and Non-Drug Technologies in Comparative Effectiveness Research. In: Sobolev B. (editor) Handbook of Health Services Research, Springer Science+Business Media New York 2015
- Boscolo PR, Canobbio M, Ciani O. La dimensione del settore dei dispositivi medici (English: How big is the medical devices market?). In: Tarricone R (a cura di) Politiche per la salute e scelte aziendali. Impatto sull’innovazione e diffusione delle tecnologie mediche (English: Health policy and trusts’ choices. The impact on innovation and diffusion of health technologies). 2012, Milano, Egea
- Boscolo PR, Ciani O, Torbica A. I processi di valutazione dei dispositive medici e delle tecnologie sanitarie (English: The assessment of health technologies). In: Tarricone R (a cura di) Politiche per la salute e scelte aziendali. Impatto sull’innovazione e diffusione delle tecnologie mediche (English: Health policy and trusts’ choices. The impact on innovation and diffusion of health technologies). 2012, Milano, Egea.
- Piccini L, Ciani O, Andreoni G. New Emerging Biomedical Technologies for Home-care and Telemedicine Applications: the Sensorwear Project. In: Campora D., editor. New Developments in Biomedical Engineering. 2010 InTech
- ARMENI, P., P. R.BOSCOLO, G.CALLEA, M. C.CAVALLO, O.CIANI, F.COSTA, S.GHISLANDI, R.TARRICONE, A.TORBICA, "Prezzi di riferimento per dispositivi medici: criticità, vantaggi e approcci" in Rapporto OASI 2018
Articles
- ELIA, E., N.STÄDLER, O.CIANI, R.TAYLOR, S.BUJKIEWICZ, "Combining tumour response and progression free survival as surrogate endpoints for overall survival in advanced colorectal cancer", Cancer Epidemiology, 2020
- CIANI, O., C. B.FEDERICI, "Value Lies in the Eye of the Patients: The Why, What, and How of Patient-Reported Outcomes Measures", Clinical Therapeutics, 2020
- PAPANIKOS, T., J. R.THOMPSON, K. R.ABRAMS, N.STÄDLER, O.CIANI, R.TAYLOR, S.BUJKIEWICZ, "Bayesian hierarchical meta-analytic methods for modeling surrogate relationships that vary across treatment classes using aggregate data", Statistics In Medicine, 2020
- BOSCOLO, P. R., G.CALLEA, O.CIANI, R.TARRICONE, "Measuring Value in Health Care: A Comparative Analysis of Value-based Frameworks", Clinical Therapeutics, 2019
- SMART, N. A., R.TAYLOR, S.WALKER, F.WARREN, O.CIANI, C. H.DAVOS, M.PIEPOLI, "Exercise training for chronic heart failure (ExTraMATCH II): Why all data are not equal", European Journal of Preventive Cardiology, 2019
- TAYLOR, R. S., S.WALKER, O.CIANI, F.WARREN, N. A.SMART, M.PIEPOLI, C. H.DAVOS, "Exercise-based cardiac rehabilitation for chronic heart failure: the EXTRAMATCH II individual participant data meta-analysis", Health Technology Assessment, 2019
- TAYLOR, R. S., S.WALKER, N. A.SMART, M. F.PIEPOLI, F. C.WARREN, O.CIANI, D.WHELLAN, C.O’CONNOR, S. J.KETEYIAN, A.COATS, C. H.DAVOS, H. M.DALAL, K.DRACUP, L. S.EVANGELISTA, K.JOLLY, J.MYERS, B. B.NILSSON, C.PASSINO, M. D.WITHAM, G. Y.YEH, "Impact of Exercise Rehabilitation on Exercise Capacity and Quality-of-Life in Heart Failure", Journal of the American College of Cardiology, 2019
- ROGNONI, C., O.CIANI, S.SOMMARIVA, I.BARGELLINI, S.BHOORI, R.CIONI, A.FACCIORUSSO, R.GOLFIERI, A.GRAMENZI, V.MAZZAFERRO, C.MOSCONI, F.PONZIANI, R.SACCO, F.TREVISANI, R.TARRICONE, "Trans-arterial radioembolization for intermediate-advanced hepatocellular carcinoma: a budget impact analysis", BMC Cancer, 2018
- TAYLOR, R. S., S.WALKER, N. A.SMART, M. F.PIEPOLI, F. C.WARREN, O.CIANI, C.O'CONNOR, D.WHELLAN, S. J.KETEYIAN, A.COATS, C. H.DAVOS, H. M.DALAL, K.DRACUP, L.EVANGELISTA, K.JOLLY, J.MYERS, R. S.MCKELVIE, B. B.NILSSON, C.PASSINO, M. D.WITHAM, G. Y.YEH, A. O.ZWISLER, ON BEHALF OF THE EXTRAMATCH II COLLABORATION, "Impact of exercise-based cardiac rehabilitation in patients with heart failure (ExTraMATCH II) on mortality and hospitalisation: an individual patient data meta-analysis of randomised trials", European Journal of Heart Failure, 2018
- Wallach JD, Ciani O, Pease AM, Gonsalves GS, Krumholz, HM, Taylor, RS, Ross JS. Comparison of treatment effect sizes from pivotal and postapproval trials of novel therapeutics approved by the FDA on the basis of surrogate markers of disease: a meta-epidemiological study, BMC Medicine (in press)
- Pallari E, Lewison G, Ciani O, Tarricone R, Sommariva S, Begum M, Sullivan R. The impacts of diabetes research from 31 European Countries in 2002 to 2013. Research Evaluation, 2018 (in press)
- Rognoni C, Ciani O, Sommariva S, Tarricone R. Cost–effectiveness analysis of treatments involving radioembolization in intermediate-stage hepatocellular carcinoma. J Comp Eff Res 2017 Dec 12. https://doi.org/10.2217/cer-2017-0050
- Stephani V, Sommariva S, Spranger A, Ciani O. Non-communicable diseases: mapping research funding organisations, funding mechanisms and research practices in Italy and Germany. Health Res Policy Syst. 2017 Oct 2;15(1):85. doi: 10.1186/s12961-017-0249-x.
- Begum M, Lewison G, Sommariva S, Ciani O, Tarricone R, Sullivan R European diabetes research and its funding, 2002-2013. Diabet Med. 2017 Jun 21. doi: 10.1111/dme.13411.
- Ciani O, Buyse M, Drummond M, Rasi G, Saad ED, Taylor RS. Time to Review the Role of Surrogate End Points in Health Policy: State of the Art and the Way Forward. Value Health. 2017 Mar;20(3):487-495. doi: 10.1016/j.jval.2016.10.011.
- Rognoni C, Ciani O, Sommariva S, Tarricone R. Real world data for the evaluation of transarterial radioembolization versus sorafenib in hepatocellular carcinoma: a cost-effectiveness analysis, Value Health. 2017 Mar;20(3):336-344. doi: 10.1016/j.jval.2016.09.2397.
- Ciani O, Wilcher B, van Giessen A, Taylor RS. Linking the regulatory and reimbursement processes for medical devices. Health Econ 2017 Feb;26 Suppl 1:13-29. doi: 10.1002/hec.3479.
- Schnell-Inderst P, Iglesias CP, Arvandi M, Ciani O, Matteucci Gothe R, Peters J, Blom AW, Taylor RS, Siebert U. Synthesis of RCT and observational data: a bias adjusted evidence synthesis of total hip replacement. Health Econ 2017 Feb;26 Suppl 1:46-69. doi: 10.1002/hec.3474.
- Ciani O, Pascarelli NA, Giannitti C, Galeazzi M, Meregaglia M, Fattore G, Fioravanti A. Mudbath therapy in addition to usual care in bilateral knee osteoarthritis: Economic evaluation alongside a randomized controlled trial. Arthritis Care Res (Hoboken). 2017 Jul;69(7):966-972. doi: 10.1002/acr.23116.
- Cervigni M, Sommariva M, Tenaglia R, Porru D, Ostardo E, Giammò A, Trevisan S, Frangione V, Ciani O, Tarricone R, Pappagallo GL. A randomized, open-label, multicenter study of the efficacy and safety of intravesical hyaluronic acid and chondroitin sulfate versus dimethyl sulfoxide in women with bladder pain syndrome/interstitial cystitis. Neurourol Urodyn. 2016 Sep 21 doi: 10.1002/nau.23091.
- Rognoni C, Ciani O, Sommariva S, Facciorusso A, Tarricone R, Bhoori S, Mazzaferro V. Transarterial radioembolization in intermediate-advanced hepatocellular carcinoma: systematic review and meta-analyses. Oncotarget 2016 Nov 1;7(44):72343-72355. doi: 10.18632/oncotarget.11644
- Ciani O, Buyse M, Drummond M, Rasi G, Saad ED, Taylor RS. Use of surrogate endpoints in healthcare policy: proposal for consistent adoption of a validation framework. Nature Rev Drug Disc 2016 Jul;15(7):516. doi: 10.1038/nrd.2016.81
- Ciani O, Arendsen E, Romancik M, Lunik R, Costantini E, Di Biase M, Morgia G, Fragalà E, Roman T, Bernat M, Guazzoni G, Tarricone R, Lazzeri M. Intravesical administration of combined hyaluronic acid (HA) and chondroitin sulphate (CS) for the treatment of female recurrent urinary tract infections: a European multicenter nested case-control study. BMJ Open. 2016 Mar 31;6(3):e009669.
- Ciani O, Cavazza M, Armeni P, Boscolo PR, Jommi C, Tarricone R. De innovatione: The concept of innovation for medical technologies and its implications for healthcare policy-making. Health Policy & Technology 2016 Mar 2016 5(1):47–64
- Ciani O, Taylor RS. Validation of surrogate end points for overall survival in advanced colorectal cancer: A harmonized approach is needed. J Clin Epidemiol. 2016 Feb;70:277-8.
- Ciani O, Wilcher B, Blankart RC, Hatz M, Prevolnik Rupel V, Slabe Erker R, Varabyova Y, Taylor RS. Health Technology Assessment of Medical Devices: A survey of non-European Union Agencies. Int J Technol Assess Health Care. 2015 Jan;31(3):154-65.
- Generali D, Venturini S, Rognoni C, Ciani O, Pusztai L, Loi S, Jerusalem G, Bottini A, Tarricone R. A network meta-analysis of everolimus plus exemestane versus chemotherapy in the first- and second-line treatment of estrogen receptor-positive metastatic breast cancer. Breast Cancer Res Treat. 2015 Jul;152(1):95-117.
- Ciani O, Buyse M, Garside R, Peter J, Saad E, Stein K, Taylor RS. Validation of surrogate outcomes for overall survival in advanced colorectal cancer: a systematic review and meta-analysis of randomised controlled trials. J Clin Epidemiol. 2015 Jul;68(7):833-842.
- Ciani O, Jommi C. The role of health technology assessment bodies in shaping drug development. Drug Des Devel Ther. 2014 Nov 10;8:2273-81.
- Taylor RS, Piepoli MF, Smart N, Coats AJ, Ellis S, Dalal H, O'Connor CM, Warren FC, Whellan D, Ciani O. Exercise training for chronic heart failure (ExTraMATCH II): Protocol for an individual participant data meta-analysis. Int J Cardiol. 2014 Apr 26. pii: S0167-5273(14)00885-7.
- Ciani O, Davis S, Tappenden P, Garside R, Stein K, Buyse M, Saad E, Taylor RS. Validation of surrogate end points in advanced solid tumours: systematic review of statistical methods, results and implication for policy-makers. Int J Tech Assessment Health Care 2014 Jul;30(3):312-24
- Ciani O, Hoyle M, Pavey T, Cooper C, Garside R, Rudin C, Taylor RS. Complete cytogenetic response and major molecular response as surrogate outcomes for overall survival in first-line treatment of chronic myelogenous leukemia: a case-study for technology appraisal on the basis of surrogate outcomes evidence. Value in Health. 2013 Sep-Oct;16(6):1081-90.
- Ciani O, Grassi D, Tarricone R. An economic perspective on urinary tract infections: the costs of resignation. Clin Drug Investig. 2013 Apr;33(4):255-61.
- Ciani O, Buyse M, Garside R, Pavey T, Stein K, Sterne JA, Taylor RS. Comparison of treatment effect sizes associated with surrogate and final patient relevant outcomes in randomised controlled trials: meta-epidemiological study. BMJ. 2013 Jan 29;346:f457.
- Ciani O, Taylor RS. Surrogate, friend or foe? The need for case studies of the use of surrogate outcomes in cost-effectiveness analyses. Health Econ. 2013 Feb;22(2):251-2.
- Pavey T, Hoyle M, Ciani O, Crathorne L, Jones-Hughes T, Cooper C, Osipenko L, Venkatachalam M, Rudin C, Ukoumunne O, Garside R, Anderson R. Dasatinib, nilotinib and standard-dose imatinib for the first-line treatment of chronic myeloid leukaemia: systematic reviews and economic analyses. Health Technol Assess. 2012;16(42):iii-iv, 1-277. doi: 10.3310/hta16420.
- Ciani O, Tarricone R, Torbica A. Diffusion and use of health technology assessment in policy making: what lessons for decentralised healthcare systems? Health Policy. 2012 Dec;108(2-3):194-202.
- Boscolo PR, Canobbio M, Ciani O. Hospital-based HTA: quale valore per la valutazione delle tecnologie nelle Aziende Sanitarie italiane? (English: Hospital-based HTA: does the assessment of health technologies matter?) Management Control, Suppl(2), 2012.
- Mota RE, Tarricone R, Ciani O, Bridges JF, Drummond M. Determinants of demand for total hip and knee arthroplasty: a systematic literature review. BMC Health Serv Res. 2012 Jul 30;12:225.
- Armeni P, Ciani O, Vella VA. Il settore dei dispositivi medici in Italia. L’impatto delle politiche pubbliche sulle performance delle imprese (English: The Italian market of medical devices: how public policies impact on companies’ performance). Azienda Pubblica, 2012; 2:217-238.
- Ciani O, Taylor RS. A more evidence based approach to the use of surrogate end points in policy making. BMJ. 2011 Oct 25;343:d6498.
- Armeni P, Ciani O, Palla I, Pierotti F, Tarricone R, Turchetti G. PDTA per la Chirurgia bariatrica: l’esperienza di sei centri italiani (English: Clinical pathways for bariatric surgery: the experience of six Italian hospitals). Mecosan, 2011. 20 (79): p. 14.
- Armeni P, Cavallo C, Ciani O, Tarricone R, Vella VA. I dispositivi medici in Italia: un settore, tanti mercati (English: The Italian market of medical devices). Mecosan, 2010. 19(76): p. 23-40.
- Cavallo MC, Ciani O, Gugiatti A, Jommi C, Ruocco G, Tarricone R. La gestione dell'innovazione tecnologica in sanità: analisi e confronto di alcune politiche regionali in Italia. (English: Managing technological innovation in the Italian Healthcare system: a comparative analysis of regional policies) Mecosan, 2010. 19(74): p. 37-65.
- Andreoni G, Mazzola M, Ciani O, Zambetti M, Romero M, Costa F, Preatoni E. Quantitative body movement and gesture assessment in ergonomics Int J of Human Factors Modelling and Simulation 2010 Vol.1, No.4, pp.390 – 405.
Conference Papers
- Ciani O, Federici C, Pecchia L. The evaluation of medical devices: are we getting closer to solve the puzzle? A review of recent trends, European Medical and Biological Engineering Conference - Nordic-Baltic Conference on Biomedical Engineering and Medical Physics EMBEC 2017, NBC 2017: EMBEC & NBC 2017, pp. 916-919
- Ciani O, Federici C, Tarricone R. Current and future trends in the HTA of medical devices, XIV Mediterranean Conference on medical and biological engineering and computing 2016. MEDICON 2016, March 31st-April 2nd 2016, Paphos, Cyprus
- Ciani O, Piccini L, Parini S, Rullo A, Bagnoli F, Marti P, Andreoni G. Pervasive technology in Neonatal Intensive Care Unit: a prototype for newborns unobtrusive monitoring. Conf Proc IEEE Eng Med Biol Soc 2008:1292-5.
